ArticleiScience2026
Dissociating neural circuits of social and prosocial reward in rat helping behavior.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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8 authors.
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Abstract
Helping behavior in rodents provides a powerful model for studying neurobiological underpinnings of prosocial motivation. Previously, rats allowed to release a trapped conspecific demonstrated prosocial motivation selectively toward ingroup members. Here, a refined version of the helping behavior test (HBT) allowed trapped rats to be freed without ensuing social contact, dissociating social from prosocial reward. In this "separated" HBT (SHBT), helping was not biased, as rats equally released ingroup and outgroup members. Whole-brain c-Fos mapping revealed a subset of the standard HBT prosocial brain network engaged in the SHBT. Observed absence of activity in the nucleus accumbens (NAc) instigated a chemogenetic investigation of this region. NAc activity was not necessary for helping, but significantly reduced affiliative behavior. The recruitment of
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