Evidence map›Paper›PMID 41660236›Full record

ArticleiScience2026

FAM65A, as a potential predictor of prognosis, promotes colorectal cancer progression via activating Ras/ERK/RSK signaling.

Yuqiu Ma, Jie Yao, Xinzhuang Shen, Shuying Wang, Gongli Tang, Xiaowen Yang, Yifei Li, Yifang Sun, Wenzhi Shen, Xiaoyuan Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuqiu MaDepartment of General Surgery, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272000, China.
Jie YaoDepartment of Oncology, Jining Hospital of Traditional Chinese Medicine, Jining 272000, China.
Xinzhuang ShenKey Laboratory of Precision Oncology in Universities of Shandong, Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Shuying WangKey Laboratory of Precision Oncology in Universities of Shandong, Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Gongli TangLocal Town Centre Health Centre of Difang, Pingyi County, Shandong Province 273306, China.
Xiaowen YangKey Laboratory of Precision Oncology in Universities of Shandong, Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Yifei LiHenan Key Laboratory of Immunology and Targeted Drugs, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, China.
Yifang SunDepartment of Ultrasound, Affiliated Hospital of Jining Medical University, Jining 272000, China.
Wenzhi ShenKey Laboratory of Precision Oncology in Universities of Shandong, Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Xiaoyuan ZhangKey Laboratory of Precision Oncology in Universities of Shandong, Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Yongming HuangDepartment of General Surgery, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research indicates that FAM65A is significantly involved in tumorigenesis. Nevertheless, the prognostic implications of FAM65A expression levels and its contribution to CRC malignant progression have yet to be elucidated. Here, we revealed that

Indexed as

CancerCell biologyMolecular biology

Identifiers

PMID41660236
PMCPMC12874459

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.