Evidence map›Paper›PMID 41660201›Full record

ArticleGlobal heart2026

Evaluation of Quality of Care in Chagas Disease Cardiomyopathy.

Pablo Elías Gulayin, Maria-Jesus Pinazo, Rachel Marcus, Caryn Bern, Eva H Clark, Maria Carmo Pereira Nunes, Bruno Ramos Nascimento, Shreya Shrikhande, Sean Taylor, Pablo Perel and 1 more

Abstract read
In one paragraph

Article in Global heart, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pablo Elías GulayinInstitute of Clinical Effectiveness and Health Policy (IECS), Argentina.ORCID 0000-0003-4709-7543
Maria-Jesus PinazoDrug for Neglected Diseases initiative, LATAM. Rio de Janeiro, Brazil.ORCID 0000-0002-4237-1075
Rachel MarcusLatin American Society of Chagas, Washington DC, United States.ORCID 0000-0002-6229-8864
Caryn BernDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco CA, United States.ORCID 0000-0001-8195-7303
Eva H ClarkDepartments of Medicine (Infectious Diseases) and Pediatrics (Tropical Medicine), Baylor College of Medicine, Houston, TX, United States.ORCID 0000-0002-0350-8753
Maria Carmo Pereira NunesDepartment of Internal Medicine, Faculdade de Medicina, and Telehealth Center and Cardiology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0001-8801-1828
Bruno Ramos NascimentoDepartment of Internal Medicine, Faculdade de Medicina, and Telehealth Center and Cardiology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-5586-774X
Shreya ShrikhandeWorld Heart Federation, Geneva, Switzerland.ORCID 0000-0001-9647-7855
Sean TaylorWorld Heart Federation, Geneva, Switzerland.ORCID 0000-0002-5031-3588
Pablo PerelWorld Heart Federation, Geneva, Switzerland.ORCID 0000-0002-2342-301X
Antonio Luiz RibeiroDepartment of Internal Medicine, Faculdade de Medicina, and Telehealth Center and Cardiology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-2740-0042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chagas disease (ChD), a neglected tropical disease caused by Objectives: We aimed to define the key components of the CCM quality of care (structure, process, and outcomes) for main clinical activities at the three levels of care. Methods: We applied the Donabedian model to define essential components of ChD care at primary, secondary, and tertiary levels. Key recommendations from the World Heart Federation (WHF) roadmap and evidence-based guidelines were used to identify core services at each level. We also examined two case studies that demonstrate successful implementation of innovative screening and management models. Results: Essential components of ChD care were identified at all levels. Primary care plays a central role in early diagnosis and timely treatment. Secondary care addresses complications through imaging and targeted therapy, while tertiary care provides advanced interventions and rehabilitation. Although structural gaps persist, the implementation of systematic processes and clearly defined outcomes is key to strengthening the quality, continuity, and equity of care. Conclusions: A comprehensive, structured approach to ChD care is essential to improving outcomes. Successful models illustrate that scalable, resource-appropriate interventions can enhance diagnosis and treatment. Integration into routine health systems, supported by universal health coverage, improved data systems, and implementation research, is critical to closing the care gap and advancing equity in cardiovascular health.

Indexed as

Chagas CardiomyopathyQuality of Health CareHumansChagas diseaseDonabedian modelhealth systemneglected diseasequality of care

Identifiers

PMID41660201
PMCPMC12879995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.