Evidence map›Paper›PMID 41660122›Full record

ArticleMaterials today. Bio2026

Engineered microalgal extracellular vesicles for efficient doxorubicin delivery and improved therapeutic efficacy in breast cancer.

Giorgia Adamo, Sabrina Picciotto, Pamela Santonicola, Paola Gargano, Estella Rao, Angela Paterna, Samuele Raccosta, Giulia Smeraldi, Carolina Paganini, Daniele P Romancino and 6 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giorgia AdamoCell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Sabrina PicciottoCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Pamela SantonicolaInstitute of Biosciences and BioResources (IBBR), National Research Council (CNR), Naples, 80131, Italy.
Paola GarganoCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Estella RaoCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Angela PaternaCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Samuele RaccostaCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Giulia SmeraldiCell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Carolina PaganiniDepartment of Chemistry and Applied Biosciences, ETH Zürich 8093, Switzerland.
Daniele P RomancinoCell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Monica SalamoneCell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Claudio RussoDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, 86100, Italy.
Paolo ArosioDepartment of Chemistry and Applied Biosciences, ETH Zürich 8093, Switzerland.
Elia Di SchiaviInstitute of Biosciences and BioResources (IBBR), National Research Council (CNR), Naples, 80131, Italy.
Mauro MannoCell-Tech HUB at Institute of Biophysics, National Research Council of Italy (CNR), Palermo, 90146, Italy.
Antonella BongiovanniCell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, 90146, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) have emerged as versatile and biocompatible nanocarriers for drug delivery, offering significant advantages over synthetic nanoparticles, which often suffer from rapid clearance, immunogenicity, and limited clinical translation. In this study, we introduce nanoalgosomes, a new class of EVs derived from the marine microalga

Indexed as

Breast cancerCaenorhabditis elegansChemotherapeuticsDoxorubicinDrug delivery systemExtracellular vesiclesNanoalgosomesTherapeutics

Identifiers

PMID41660122
PMCPMC12874330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.