Evidence map›Paper›PMID 41660092›Full record

ArticlePeerJ2026

Comparative metabolomics reveals organ-specific discrepancy in TCMSP-predicted bioactive ingredients between two geographically distinct regions of

Wanbo Zhang, Xinjie Jin, Ying Zhang, Luhan Peng, Haifeng Wang, Yongqun Chen, Yonghua Zhang

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wanbo Zhang *College of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.
Xinjie Jin *College of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.
Ying ZhangCollege of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.
Luhan PengCollege of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.
Haifeng WangCollege of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.
Yongqun ChenGuoxi Middle School, Ouhai District, Wenzhou, Zhejiang, China.
Yonghua ZhangCollege of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The geographical region and organ-specific accumulation of metabolites in medicinal plants are critical determinants of their pharmaceutical efficacy. Methods and Results: This study combined widely targeted metabolomics with the Traditional Chinese Medicine System Drug Analysis Platform (TCMSP) to investigate the accumulation patterns of medicinal ingredients in the leaves and roots of fresh Conclusion: These findings highlight the critical role of geographic and organ-specific factors in determining the metabolic profiles of

Indexed as

Drugs, Chinese HerbalMetabolomicsRehmanniaAnimalsChinaMedicine, Chinese TraditionalPlant LeavesPlant RootsDrugs, Chinese HerbalComparative analysisGeographical originMetabolomeOrgan-specificPharmaceutical functionRehmannia chingii

Identifiers

PMID41660092
PMCPMC12880092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.