Evidence map›Paper›PMID 41660030›Full record

ArticleJournal of conservative dentistry and endodontics2026

Plasmid-linked virulence genes and high-level gentamicin resistance in

Alexandra Castillo-Guevara, Adriana Rodriguez-Ciodaro, Catalina Méndez-De la Espriella, Oscar E Gomez-Cárdenas, Nidia E de León-Frías, Hugo Díez-Ortega

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Sessile growth on human dentine is associated withJournal of conservative dentistry and endodontics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra Castillo-GuevaraCenter for Dental Research, Faculty of Dentistry, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Adriana Rodriguez-CiodaroCenter for Dental Research, Faculty of Dentistry, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Catalina Méndez-De la EspriellaEndodontic Program, NOVA Southeastern University College of Dental Medicine, Fortlauderdale, Florida, USA.
Oscar E Gomez-CárdenasDepartment of Internal Medicine, Faculty of Medicine, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Nidia E de León-FríasFaculty of Health Sciences, School of Dentistry, Universidad Nacional Pedro Henríquez Ureña, Santo Domingo, National District, Dominican Republic.
Hugo Díez-OrtegaDepartment of Microbiology, Infectious Diseases Research Group, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To evaluate the relationship between plasmid-mediated aminoglycoside resistance, including silent resistance to high-level gentamicin resistance (HLGR), and the virulence genes aggregation substance ( Materials and Methods: Antimicrobial identification and susceptibility testing were performed using the MicroScan system. HLGR resistance, including silent phenotypes, was assessed by synergy tests and conventional polymerase chain reaction (PCR) targeting the bifunctional Statistical Analysis: Mixed clustering analysis was applied, combining mixed data factor analysis (MDFA) with hierarchical Ward and K-means methods, to identify recurrent combinations of virulence genes associated with resistance phenotypes. Statistical analysis performed by IBM SPSS Statistics, V 26.0 (IBM Corp., Armonk, NY, USA). Results: Conclusion: The coexistence of HLGR resistance and virulence genes supports a possible mechanism of plasmid co-selection in

Indexed as

Drug resistanceEnterococcus faecalisgentamicinsmicrobialplasmidsvirulence factors

Identifiers

PMID41660030
PMCPMC12880788

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.