Evidence map›Paper›PMID 41659952›Full record

SynthesisCanadian respiratory journal2026

The Effectiveness of Respiratory Muscle Training on the Duration and Severity of Respiratory Symptoms in Patients With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.

Zhenghao Yu, Hui Huang, Si Fang, Li Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Canadian respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhenghao YuDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 443600, China, hust.edu.cn.ORCID 0009-0003-5856-532X
Hui HuangDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 443600, China, hust.edu.cn.ORCID 0009-0001-4558-7453
Si FangDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 443600, China, hust.edu.cn.ORCID 0009-0009-8659-3698
Li ZhangDepartment of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 443600, China, hust.edu.cn.ORCID 0009-0000-0296-2041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effectiveness of respiratory muscle training (RMT) on respiratory symptom severity and symptom duration in adults with chronic obstructive pulmonary disease (COPD) and to appraise the certainty of the evidence. Methods: We searched seven databases and included parallel-group randomized controlled trials (RCTs) comparing RMT plus guideline-based care versus control. Meta-analyses were conducted in RevMan using fixed- or random-effects models as appropriate. Risk of bias was assessed using RoB 2. Certainty of evidence was assessed using the GRADE approach. Because multiple outcomes were analysed, we controlled the false discovery rate using the Benjamini-Hochberg (BH) procedure across prespecified meta-analysed outcomes and report both unadjusted and BH-adjusted Results: Seven RCTs ( Conclusion: In adults with COPD, adding RMT to guideline-based care probably reduces dyspnoea and improves health-related quality of life (moderate certainty). Evidence for benefits on overall symptom burden, lung function, and exercise capacity is low to very low, and the effect on symptom duration remains unknown due to the lack of reporting.

Indexed as

Breathing ExercisesPulmonary Disease, Chronic ObstructiveRespiratory MusclesDyspneaHumansQuality of LifeRandomized Controlled Trials as TopicSeverity of Illness Indexchronic obstructive pulmonary diseaserespiratory muscle trainingrespiratory symptomssymptom severity

Identifiers

PMID41659952
PMCPMC12878794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.