Evidence map›Paper›PMID 41659949›Full record

ArticleClinical case reports2026

Olanzapine Overdose-Induced Bradycardia in a Young Adult With Major Depressive Disorder: A Case Report and Literature Review.

Mohammad Ghasemi Palangi, Hassan Ahangar, Nona Sakhaie, Payman Yasami

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad Ghasemi PalangiDepartment of Cardiology, School of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science Zanjan Iran.
Hassan AhangarDepartment of Cardiology, School of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science Zanjan Iran.
Nona SakhaieSchool of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science Zanjan Iran.
Payman YasamiStudent Research Committee, Department of Cardiology, School of Medicine Zanjan University of Medical Science Zanjan Iran.ORCID https://orcid.org/0000-0002-4366-649X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olanzapine, an atypical antipsychotic widely used for psychiatric disorders, is typically associated with tachycardia and QT prolongation in overdose, while bradycardia remains a rare and underrecognized effect. We report a 20-year-old woman with major depressive disorder who presented 4 h after ingesting 100 mg of olanzapine in a suicide attempt. She exhibited marked sinus bradycardia (41 bpm) with stable hemodynamics and no QT prolongation. Laboratory and toxicology results were unremarkable. Supportive care, including oxygen, fluids, and cardiac monitoring, led to complete recovery within 48 h. This case highlights isolated bradycardia as an uncommon but important manifestation of olanzapine toxicity. Clinicians should consider bradycardia in the cardiovascular spectrum of olanzapine overdose and ensure vigilant monitoring to prevent potential complications.

Indexed as

atypical antipsychoticsbradycardiacardiac toxicitycase reportolanzapine overdose

Identifiers

PMID41659949
PMCPMC12881192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.