Evidence map›Paper›PMID 41659738›Full record

ArticlePhenomics (Cham, Switzerland)2025

Protocol for Retinal Imaging and Extraction of Imaging-Derived Phenotypes from the Chinese Human Phenome Project.

Lizhen Lan, Binxin Xu, Zhiqiang Yan, Yating Tang, Shengli Shen, Xuan Lan, Yidan Gao, Jianhua Jin, Yan Zheng, Chengyan Wang and 2 more

Abstract read
In one paragraph

Article in Phenomics (Cham, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lizhen LanHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID https://orcid.org/0000-0001-6422-6963
Binxin XuHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID https://orcid.org/0000-0003-0123-9374
Zhiqiang YanHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID https://orcid.org/0000-0003-4714-2076
Yating TangDepartment of Ophthalmology and Vision Science, Eye, ENT Hospital of Fudan University, Shanghai, 200031 China.ORCID https://orcid.org/0000-0001-5588-1667
Shengli ShenHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0009-0000-9462-8904
Xuan LanHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0009-0008-7296-1253
Yidan GaoHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-7519-7229
Jianhua JinHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0001-9617-8257
Yan ZhengHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0003-1129-3147
Chengyan WangHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-8890-4973
Jingchun LuoHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0001-5138-6458
Mei TianHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-1587-2114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal imaging is pivotal in the evaluation of ocular and systemic health, presenting significant promise for extensive population studies. However, the lack of standardized and automated techniques for extracting Imaging-Derived Phenotypes (IDPs) from retinal images is a major impediment. To counteract this challenge, the Chinese Human Phenome Project (CHPP) has developed a comprehensive protocol that includes Quality Control (QC), preprocessing, and automated or semi-automated extraction of IDPs from fundus photography and Optical Coherence Tomography (OCT) images. This protocol incorporates Artificial Intelligence (AI)-based methods to achieve accurate and efficient IDP extraction, facilitating standardized analysis of large-scale populations. We hope that this Standard Operating Procedure (SOP) guideline will impart valuable insights for ophthalmology-related disciplines and provides support for future research endeavors utilizing retinal imaging data. Supplementary Information: The online version contains supplementary material available at 10.1007/s43657-023-00155-5.

Indexed as

Chinese Human Phenome ProjectImaging-Derived PhenotypesProtocolRetinal imaging

Identifiers

PMID41659738
PMCPMC12881225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.