Evidence map›Paper›PMID 41659737›Full record

ArticlePhenomics (Cham, Switzerland)2025

Reduced Usage of

Xueping Li, Yuxin Li, Dong Ding, Baiyun Xie, Jun Yao, Yu Chen, Zhaozhao Zhao, Peng Yu, Shengwei Zhang, Fu Yang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Phenomics (Cham, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xueping Li *State Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.ORCID 0000-0002-6996-1972
Yuxin Li *State Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Dong DingState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Baiyun XieState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Jun YaoState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.ORCID 0000-0002-5970-8375
Yu ChenState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Zhaozhao ZhaoState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.ORCID 0000-0002-5800-4077
Peng YuState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Shengwei ZhangState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.
Fu YangDepartment of Medical Genetics, Second Military Medical University, Shanghai, 200433 P.R. China.
Ting NiState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.ORCID 0000-0001-7007-1072
Gang WeiState Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Collaborative Innovation Center of Genetics and Development, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Huashan Hospital, Human Phenome Institute, Fudan University, Shanghai, 200438 China.ORCID 0000-0003-1442-3920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alternative polyadenylation (APA) of mRNA is a widespread transcriptomic mechanism which fine-tunes gene expression and plays important roles in diverse biological processes. Of the different APA types, intronic polyadenylation is a prevalent but not well understood one. Although the upstream regulation of intronic polyadenylation is extensively investigated, the understanding of its biological function largely lags behind. Here, we discovered that intronic polyadenylation of glutaminase-encoding gene Supplementary Information: The online version contains supplementary material available at 10.1007/s43657-024-00198-2.

Indexed as

Alternative Polyadenylation (APA)Cellular SenescenceGlutaminaseIntronic PolyadenylationMitochondria

Identifiers

PMID41659737
PMCPMC12881237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.