ArticleFrontiers in aging neuroscience2025
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- What's in a name? reframing advanced Parkinson's disease as a multidimensional state.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Frailty is significantly more prevalent in individuals with Parkinson's disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aimed to characterize the clinical features and cerebral metabolic patterns of frail PD patients using [ Methods: A total of 64 PD patients treated at Shenzhen People's Hospital underwent Results: Among the PD cohort (mean age: 66.86 ± 6.97 years; 30 female), 34 were classified as non-frail (mean age: 64.29 ± 6.61 years; 16 female) and 30 as frail (mean age: 69.77 ± 6.17 years; 14 female). Compared to the non-frail group, frail PD patients were significantly older ( Conclusion: Frailty in PD is associated with advanced age, greater motor severity, and possibly increased medication needs. Frail PD patients exhibit specific patterns of cerebral hypometabolism and more severe cognitive deficits. Distinct brain regions are differentially associated with specific cognitive domains. Notably, reduced metabolism in the Temporal_Inf_R is significantly related to motor symptom severity in frail PD, suggesting a key region in the pathophysiology of frailty in PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.