ArticlebioRxiv : the preprint server for biology2026
Translesion DNA synthesis on pyrimidine dimers by Plant organellar DNA polymerases is metal-dependent.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Ultraviolet (UV) radiation generates crosslinked DNA lesions-primarily cyclobutane pyrimidine dimers (CPDs) and [6-4] photoproducts ([6-4] PPs)-that block the progression of replicative DNA polymerases. In plants, these lesions are efficiently removed from nuclear DNA by dedicated repair pathways; however, comparable repair mechanisms are absent in plastids and mitochondria. Consequently, how plant organellar DNA polymerases (POPs) tolerate or bypass UV-induced damage has remained unclear. Here, we show that the two GRAPHICAL ABSTRACT:
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