Evidence map›Paper›PMID 41659587›Full record

ArticlebioRxiv : the preprint server for biology2026

Epithelial Reprogramming and Transition during Pulmonary Bioengineering.

Satoshi Mizoguchi, Vi Lee, Hahram Kim, Sophie E Edelstein, Nuoya Wang, Maria Tomas Gracia, Colten Danelski, Connor Haynes, Rachel Rivero, David Stitelman and 6 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Satoshi MizoguchiDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Vi LeeDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Hahram KimDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Sophie E EdelsteinDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Nuoya WangDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Maria Tomas GraciaDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.
Colten DanelskiDepartment of Biomedical Engineering, Yale University, New Haven, CT 06511, USA.
Connor HaynesVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT 06520, USA.
Rachel RiveroVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT 06520, USA.
David StitelmanDepartment of Surgery, Yale School of Medicine, New Haven, CT 06520, USA.
Tomohiro ObataVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT 06520, USA.
Allison M GreaneyDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Tomoshi TsuchiyaDepartment of Thoracic Surgery, University of Toyama, Toyama, 9300194, Japan.
Themis R KyriakidesVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT 06520, USA.
Naftali KaminskiDepartment of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0001-5917-4601
Micha Sam Brickman RaredonDepartment of Anesthesiology, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-1441-6122

Funding

Research Training in AnesthesiaT32GM086287 · NIGMS · YALE UNIVERSITY · PI ROBERT SCHONBERGER · 2009 to 2026
$3.7M
NIGMS NIH HHS T32 GM086287
6 · The paper itself

Abstract

Recent research has emphasized the critical role of cell state transitions in tissue homeostasis. In lung biology, transitional cells are recognized as a feature of tissue-scale processes during both normal physiology and disease. The precise way that transitional cell states emerge and are regulated remains to be determined. Engineered tissues, built in a laboratory through bioengineering approaches, allow detailed study of cellular states that are not commonly found in native biology, and allow opportunities to directly induce and manipulate cellular transitions. The following study explores and characterizes epithelial cell states that emerge via cellular reprogramming in a tissue engineering context.

Identifiers

PMID41659587
PMCPMC12873878

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.