Evidence map›Paper›PMID 41659542›Full record

ArticlebioRxiv : the preprint server for biology2026

Native yeast kinetochore structures identify an essential inner kinetochore interaction.

Mengqiu Jiang, Changkun Hu, Sabrine Hedouin, Angelica Andrade Latino, Yasuhiro Arimura, Andrew B Stergachis, Sue Biggins

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mengqiu JiangHoward Hughes Medical Institute, Division of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Changkun HuHoward Hughes Medical Institute, Division of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Sabrine HedouinDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Angelica Andrade LatinoDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Yasuhiro ArimuraDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Andrew B StergachisDivision of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, United States of America.ORCID 0000-0002-1299-3674
Sue BigginsHoward Hughes Medical Institute, Division of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.ORCID 0000-0002-4499-6319

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Mechanisms underlying chromosome segregationR35GM149357 · NIGMS · FRED HUTCHINSON CANCER CENTER · PI Susan Biggins · 2023 to 2026
$1.5M
NCI NIH HHS P30 CA015704NIGMS NIH HHS R35 GM149357
6 · The paper itself

Abstract

Kinetochores must accurately assemble on centromeres every cell cycle for faithful chromosome segregation. Although a conserved centromeric histone variant is essential for inner kinetochore formation, the budding yeast centromeric DNA is a poor template for nucleosome formation

Indexed as

CentromereChromosome segregationDNA bendingKinetochoreNdc10

Identifiers

PMID41659542
PMCPMC12873945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.