Evidence map›Paper›PMID 41659500›Full record

ArticlebioRxiv : the preprint server for biology2026

Lineage-specific

Nicole A P Lieberman, Luciana N Garcia, Shah A K Mohamed Bakhash, Jeffrey C Furlong, B Ethan Nunley, Andrés Rabinovich, Patricia Fernandez Pardal, Viviana Leiro, Hong Xie, Farhang Aghakhanian and 14 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Nicole A P LiebermanDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0001-9334-8150
Luciana N GarciaServicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina.
Shah A K Mohamed BakhashDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Jeffrey C FurlongDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
B Ethan NunleyDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Andrés RabinovichServicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina.
Patricia Fernandez PardalHospital de Infecciosas F J Muñiz, Servicio de Dermatología, Buenos Aires City, Argentina.
Viviana LeiroHospital de Infecciosas F J Muñiz, Servicio de Dermatología, Buenos Aires City, Argentina.
Hong XieDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Farhang AghakhanianInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mauro Romero Leal PassosDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Wilma Nancy Campos ArzeDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Hugo Boechat AndradeDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Silver K VargasCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Lima, Peru.
Kelika A KondaCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Lima, Peru.
Michael Reyes DiazCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Lima, Peru.
Carlos CaceresCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Lima, Peru.
Jeffrey D KlausnerKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jonathan B ParrInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Arlene SeñaInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ariyaratne ManathungeNational STD/AIDS Control Programme, Ministry of Health, Colombo, Sri Lanka.
Lorenzo GiacaniDepartment of Medicine, Division of Allergy and Infectious Diseases, Harborview Medical, Center, University of Washington, Seattle, WA, USA.
Jaime AltchehServicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina.
Alexander L GreningerDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0002-7443-0527

Funding

Syphilis Immunology and Biology to Improve Clinical Management and Vaccine DesignR01AI139265 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jeffrey David Klausner · 2018 to 2026
$4.8M
Gates Foundation INV-036560NIAID NIH HHS R01 AI139265
6 · The paper itself

Abstract

Background: Syphilis rates are rising globally, with increases in congenital syphilis in South America particularly concerning. The characterization of contemporary South American Methods: People with primary, secondary, or congenital syphilis were enrolled at two clinics in Buenos Aires between October 2018 and January 2023, including individuals associated with intra-household transmission. Hybrid capture WGS was performed and a core genome phylogeny generated. K-mer-based methods using full-length Findings: Interpretation: Funding: Gates Foundation INV-036560 (A.S.); NIH/NIAID R01AI139265 (J.D.K).

Identifiers

PMID41659500
PMCPMC12874013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.