Evidence map›Paper›PMID 41659494›Full record

ArticlebioRxiv : the preprint server for biology2026

Deep Learning-Based Spatial Immunoprofiling of Multiplex Immunofluorescence Images Distinguishes Tuberculosis Disease States in Diversity Outbred Mice.

Usama Sajjad, Nicholas A Crossland, Metin N Gurcan, Gillian Beamer, Muhammad Khalid Khan Niazi

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Usama SajjadDepartment of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0002-7262-3034
Nicholas A CrosslandNational Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA, USA.ORCID 0000-0003-3873-9188
Metin N GurcanCenter for Artificial Intelligence Research, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Gillian BeamerTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0001-6782-4424
Muhammad Khalid Khan NiaziDepartment of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

Funding

Predicting tuberculosis outcomes using genotypic and biomarker signaturesR01HL145411 · NHLBI · TUFTS UNIVERSITY BOSTON · PI BEAMER, GILLIAN L · 2019 to 2023
$3.4M
An ensemble deep learning model for tumor bud detection and risk stratification in colorectal carcinoma.R01CA276301 · NCI · OHIO STATE UNIVERSITY · PI Wei Chen, Muhammad Khalid Khan Niazi · 2023 to 2026
$2.0M
Vectra Polaris Quantitative Pathology Imaging SystemS10OD030269 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CROSSLAND, NICHOLAS ALEXANDER · 2021 to 2021
$402k
Ventana Discovery Ultra Research Autostainer: an Ex+ Core serviceS10OD026983 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CROSSLAND, NICHOLAS ALEXANDER · 2019 to 2019
$207k
NCI NIH HHS R01 CA276301NHLBI NIH HHS R01 HL145411NIH HHS S10 OD026983NIH HHS S10 OD030269
6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Identifiers

PMID41659494
PMCPMC12874044

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.