ArticleEuropean oral research2026
Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin.
Article in European oral research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effect of boric acid intracanal medicament in hydrogel form on root canal sealer penetration.European oral research · 2026Article
- Influence of endodontic irrigants on hydraulic cements: solubility, color alteration and surface changes.European oral research · 2026Article
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Authors and funding
4 authors.
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Abstract
Purpose: This study aimed to evaluate the effects of three final irrigation solutions with chelation properties [ethylenediaminetetraacetic acid (EDTA), novel silver citrate (NSC), and nanochitosan] on root canal dentin erosion and mineral content (calcium-to-phosphorus ratio (Ca/P ratio). Materials and methods: A total of 28 premolars were used and assigned to four groups (n = 7): Group 1 17% EDTA; Group 2: NSC; Group 3: 0.2% nanochitosan; Group 4: saline (control). Each group was finally irrigated with a volume of 1 ml/min until the total final irrigation was performed for 5 min using a 30-gauge side vented needle, and the needle was inserted 1 mm shorter than the working length. Irrigation solution pH was netral. Each tooth was then divided into two parts: mesial and distal. The mesial section was evaluated for root canal dentin erosion, whereas the distal section was analyzed for the Ca/P ratio. Each section was evaluated at three levels (coronal, middle, and apical) of the root canal. Data on root canal erosion were analyzed using the Kruskal-Wallis and Mann-Whitney U tests, whereas the Ca/P ratio was analyzed using one-way ANOVA and Tukey's test. Results: The EDTA-treated group exhibited the highest erosion, whereas the nanochitosan-treated group exhibited the lowest erosion of the root canal dentin (p<0.05). The nanochitosan-treated group exhibited the highest Ca/P ratio, whereas the EDTA-treated group exhibited the lowest ratio (p<0.05). The apical level had the highest Ca/P ratio but the lowest erosion compared with the other levels (p<0.05). Conclusion: Nanochitosan demonstrated the lowest erosion and highest Ca/P ratio at all root canal dentin levels. Therefore, nanochitosan can potentially be used as a final irrigation solution.
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