Evidence map›Paper›PMID 41659094›Full record

ReviewReviews in cardiovascular medicine2026

4D-Flow Cardiac Magnetic Resonance Imaging: An 8-Year Clinical Practice Review.

Javier Urmeneta Ulloa, Vicente Martínez de Vega, Isabel Molina Borao, Ana Álvarez Vázquez, Julia López Alcolea, Manuel Recio Rodríguez, José Ángel Cabrera

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Javier Urmeneta UlloaCardiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.ORCID https://orcid.org/0000-0001-6968-3741
Vicente Martínez de VegaRadiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.
Isabel Molina BoraoPediatric Cardiology Department, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Ana Álvarez VázquezRadiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.
Julia López AlcoleaRadiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.
Manuel Recio RodríguezRadiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.
José Ángel CabreraCardiology Department, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four-dimensional (4D) flow cardiac magnetic resonance (CMR) is an advanced imaging modality that enables comprehensive qualitative and quantitative assessment of blood flow in the three spatial dimensions plus time. This technique is more accurate, reproducible, and easier to interpret visually than conventional two-dimensional phase-contrast techniques. In this narrative review, we synthesize our clinical experience-including practical insights from representative cases from routine practice-with published research to describe the technical foundations, clinical applications, advantages, and limitations of this technique. We discuss the technical aspects, including spatial and temporal resolution, velocity encoding, contrast administration, workflow requirements, and post-processing software, and their influence on diagnostic performance. Thus, 4D-flow CMR imaging can accurately assess cardiac shunts through advanced visualization of pathlines and streamlines, providing direct quantification of pulmonary flow: systemic flow ratios, blood flow volumes, and complex hemodynamic patterns in congenital heart disease (CHD). Moreover, 4D-flow CMR imaging provides robust characterization of valvular and aortic disease through dynamic flow analysis and quantitative hemodynamic metrics. Overall, 4D flow CMR imaging is a powerful, noninvasive diagnostic tool that can greatly enhance clinical decision-making. The growing body of evidence supports the use of 4D-flow CMR imaging in routine clinical practice, particularly for evaluating CHD and valvular and aortic disorders.

Indexed as

4D-flowaortic disorderscardiac magnetic resonancecongenital heart diseasevalvular heart disease

Identifiers

PMID41659094
PMCPMC12873672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.