Evidence map›Paper›PMID 41659085›Full record

ReviewReviews in cardiovascular medicine2026

Caspase Recruitment Domain Family Member 8: A Favorable Target in the Pathogenesis of Atherosclerosis.

Dandan Tian, Li Liu, Guang-Gui Zeng, Jinrong He, Huiqin Liu, Dandan Ma, Zixin Yang, Xiangyan Ma, Yunxiang Cao, Chunyan Xu

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. PeerJ · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dandan TianDepartment of Intensive Care Medicine, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0000-1008-4728
Li LiuDepartment of Nursing, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0006-0828-2155
Guang-Gui ZengSchool of Medicine, Shanghai Jiao Tong University, 200127 Shanghai, China.ORCID https://orcid.org/0000-0002-0219-2451
Jinrong HeDepartment of Cardiology, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0009-0334-0143
Huiqin LiuDepartment of Intensive Care Medicine, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.
Dandan MaDepartment of Intensive Care Medicine, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0005-4857-8746
Zixin YangDepartment of Cardiology, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0002-2073-0097
Xiangyan MaDepartment of Cardiology, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0005-1150-759X
Yunxiang CaoDepartment of Cardiology, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0007-1523-1062
Chunyan XuDepartment of Cardiology, Hunan University of Medicine General Hospital, 418000 Huaihua, Hunan, China.ORCID https://orcid.org/0009-0002-3417-7632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis, a lipid-driven chronic inflammatory disease, is the primary pathological basis of cardiovascular diseases, characterized by endothelial injury, lipid deposition, immune cell infiltration, and chronic inflammation. The NOD-like Receptor Pyrin Domain-Containing 3 (

Indexed as

atherosclerosisCARD8cardiovascular diseasemolecular mechanismstherapeutic potential

Identifiers

PMID41659085
PMCPMC12873704

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.