Evidence map›Paper›PMID 41658807›Full record

ReviewCureus2026

Expert Opinion on the First-Line Management of Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema in India: The Role of Faricimab.

Chaitra Jayadev, Dinesh Talwar, Muna Bhende, Raja Narayanan, Vishali Gupta, Debdulal Chakraborty, Satyen Deka, George Manayath, Alay Banker

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chaitra JayadevVitreo Retina, Narayana Nethralaya Eye Institute, Bengaluru, IND.
Dinesh TalwarVitreo Retina, Center For Sight, Delhi, IND.
Muna BhendeVitreo Retina, Sankara Nethralaya, Chennai, IND.
Raja NarayananVitreo Retina, Flaum Eye Institute, University of Rochester, New York, USA.
Vishali GuptaVitreo Retina, Post Graduate Institute of Medical Education and Research, Chandigarh, IND.
Debdulal ChakrabortyVitreo Retina, Disha Eye Hospital, Hooghly, IND.
Satyen DekaVitreo Retina, ASG Eye Hospital, Guwahati, IND.
George ManayathVitreo Retina, Aravind Eye Hospital, Coimbatore, IND.
Alay BankerVitreo Retina, Banker Retina Center, Ahmedabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This expert opinion article summarizes deliberations from a focused panel discussion involving nine retina specialists on the clinical utility of faricimab in managing neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). The discussion explored evolving understanding of the multifactorial disease mechanisms, including pathways beyond vascular endothelial growth factor-A, and the rationale for dual inhibition strategies. Experts shared their clinical perspectives on faricimab use in diverse patient profiles, treatment sequencing, and individualized dosing approaches to achieve durable disease control. Practical considerations around early initiation, optimization of treatment intervals, and real-world applicability were also discussed. The insights highlight expert-derived strategies for integrating faricimab as a first-line treatment into clinical practice, emphasizing its role in achieving vascular stability and the improved durability of treatment response. Overall, the panel concluded that faricimab represents a clinically valuable first-line therapeutic option for nAMD and DME, enabling individualized, durable disease control in routine practice.

Indexed as

angiopoietin-2diabetic macular edemafaricimabneovascular age-related macular degenerationtreat-and-extend regimen

Identifiers

PMID41658807
PMCPMC12874185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.