ArticleCureus2026
Changing Battlelines: 12-Month Antimicrobial Resistance Trends at a Tertiary Care Hospital in Nagpur, Maharashtra, India.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe global surge in antimicrobial resistance (AMR) presents a significant public health threat, especially in developing nations like India with high infectious disease burdens and unregulated antibiotic use. Surveillance of bacterial pathogens and their resistance profiles is essential to inform empirical treatment and formulate antibiotic stewardship policies. This study was conducted to evaluate the bacteriological profile and antimicrobial resistance patterns of clinical isolates over a 12-month period at a tertiary care hospital. The findings aim to guide empirical antibiotic therapy and strengthen hospital antibiotic stewardship policies through the development of a local antibiogram.
methodsA retrospective, observational study was conducted in the Microbiology Laboratory of Indira Gandhi Government Medical College and Hospital in Nagpur, Maharashtra, India, from May 2024 to April 2025. Out of a total of 22,125 clinical specimens, 4603 (22.87%) were bacterial culture positive, and identification was done using standard conventional microbiological procedures. Antimicrobial susceptibility testing (AST) was performed in accordance with the Clinical and Laboratory Standards Institute (CLSI) guidelines M100 and M45 for
resultsOf the total samples, 4603 (22.87%) yielded positive cultures. Gram-negative organisms predominated (80.42%). Among these,
conclusionThe study reveals a high prevalence of multidrug-resistant organisms in clinical samples, emphasizing the urgent need for routine surveillance, infection control measures, and rational antibiotic usage. Data generated from such studies can guide empirical therapy and help to develop regional antibiograms.
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