ArticleCureus2026
Racial Disparities in Severe Cutaneous Adverse Reactions: A Report of Two Cases on Preventable Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Prescription Errors Through Medication Stewardship.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe, life-threatening cutaneous adverse reactions often triggered by medications. Common medications implicated in SJS and TEN include antibiotics, anticonvulsants, allopurinol, and nonsteroidal anti-inflammatory drugs (NSAIDs). Polypharmacy, particularly inappropriate or unnecessary medication use, increases the risk of severe adverse drug reactions. We present a case report discussing two patients with SJS/TEN secondary to non-indicated medication administration. The first patient was a 28-year-old male with antibiotic-related SJS after receiving amoxicillin-clavulanate for fungal balanitis. The second patient was a 54-year-old male with allopurinol-induced TEN despite no history of gout or hyperuricemia. These cases underscore the importance of medication stewardship, careful medication reconciliation, and clear communication between patients and providers.
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