Evidence map›Paper›PMID 41658682›Full record

ArticleCureus2026

Clinical Presentation and Management of Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Series.

João Cunha, Rita Afonso, Roberto Calças Marques, Ana Cabrita, Ana Paula Silva

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

João CunhaNephrology Department, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Rita AfonsoNephrology Department, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Roberto Calças MarquesNephrology Department, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Ana CabritaNephrology Department, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Ana Paula SilvaNephrology Department, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare systemic inflammatory condition characterized by oculorenal involvement. The pathophysiology is not fully understood but is thought to involve an immune-mediated response, potentially triggered by infections, medications, or genetic factors. TINU syndrome is often challenging to diagnose due to the asynchronous presentation of ocular and renal manifestations, requiring the exclusion of other systemic diseases. We present a four-case series of TINU syndrome, diagnosed between 2014 and 2024 at a tertiary center, highlighting the diversity in clinical presentations and outcomes, with the aim of bringing the authors' experience in the diagnosis and management of this still underrecognized syndrome.

Indexed as

corticosteroidsinflammationtinu syndrometubulointerstitial nephritistubulointerstitial nephritis and uveitis syndromeuveitis

Identifiers

PMID41658682
PMCPMC12882806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.