Evidence map›Paper›PMID 41658650›Full record

ArticleCureus2026

Biopsy Diagnosis Challenges in Oral Carcinoma Cuniculatum: A Case Report.

Shingo Kodama, Takayuki Kurimoto, Takasuke Usuki, Yuichiro Hamamoto, Shoichiro Ishii

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shingo KodamaDepartment of Oral and Maxillofacial Surgery, Osaka University, Suita, JPN.
Takayuki KurimotoDepartment of Oral and Maxillofacial Surgery, Kinki Central Hospital, Itami, JPN.
Takasuke UsukiDepartment of Oral and Maxillofacial Surgery, Kinki Central Hospital, Itami, JPN.
Yuichiro HamamotoDepartment of Pathology, Kinki Central Hospital, Itami, JPN.
Shoichiro IshiiDepartment of Oral and Maxillofacial Surgery, Kinki Central Hospital, Itami, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral carcinoma cuniculatum (OCC) is an extremely rare variant of squamous cell carcinoma that often poses diagnostic difficulties on biopsy despite clinical indications of malignancy. We report the case of a 90-year-old woman who presented with a granular endophytic lesion on the maxillary gingiva, accompanied by numerous fistulas exuding white, keratin-like material. Computed tomography revealed marked bone resorption. Although two initial biopsies were inconclusive, a third biopsy targeting deeper tumor tissue adjacent to the resorbed bone confirmed the diagnosis of OCC. The presence of keratin-like discharge from the tumor may be a diagnostic clue, and obtaining tissue from deeply infiltrated regions is essential for accurate diagnosis.

Indexed as

biopsyfistulagingivakeratin dischargeoral carcinoma cuniculatum

Identifiers

PMID41658650
PMCPMC12872586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.