ArticleFrontiers in plant science2025
Integrated transcriptomic, untargeted and targeted metabolomic analyses reveal seasonal regulatory mechanisms of vascular cambium activity in woody plants: insights from
Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: The vascular cambium is a pivotal tissue that drives secondary growth in woody plants, directly determining wood structure and properties. Methods: To elucidate the underlying molecular and metabolic regulatory mechanisms, we integrated untargeted metabolomics, lignin-targeted metabolomics, and transcriptomic analyses. Results: Untargeted metabolomic profiling identified 2,178 differentially synthesised metabolites (DSMs), predominantly associated with amino acid metabolism, fatty acid metabolism, phenylpropanoid biosynthesis (PB), and plant hormone signal transduction (PHST). Lignin-targeted metabolomics detected 8 DSMs, most of which initially increased and subsequently declined, peaking in August, with the exception of sinapyl alcohol and L-phenylalanine. Transcriptomic analysis identified 19,609 differentially expressed genes (DEGs), primarily enriched in PB and PHST pathways. Key PB-related structural genes, including Discussion: These findings provide a comprehensive framework for understanding seasonal cambial activity in
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