Evidence map›Paper›PMID 41658482›Full record

ArticleJournal of surgical case reports2026

Treatment of toxic epidermal necrosis lesions with ovine forestomach matrix.

Rodrigo Dornelles, Jessica Simon, Sabraj O C Dutra

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rodrigo DornellesPlastic Surgery, Hospital Beneficência Portuguesa de São Paulo, Rua Maestro Cardim 69, São Paulo 01323-000, Brazil.
Jessica SimonAroa Biosurgery Limited, 64 Richard Pearse Drive Auckland, 2022,  New Zealand.
Sabraj O C DutraPlastic Surgery, Hospital Beneficência Portuguesa de São Paulo, Rua Maestro Cardim 69, São Paulo 01323-000, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stevens-Johnson syndrome and toxic epidermal necrosis (TEN) are used to describe a spectrum of acute mucocutaneous reactions primarily affecting the skin and mucous membranes, resulting in painful blisters and epidermal detachment. Swift diagnosis followed by management of the damaged epidermis is vital to prevent further infection, which if left untreated can become life-threatening. We report a case of TEN in a 42-year-old female who presented with 55% epidermal loss. Over the course of 41 days, the affected regions were treated with ovine forestomach matrix (OFM) grafts, which led to epithelial restoration of the lesions in 1-2 weeks with good functional and cosmetic outcomes. This case is the first documented use of OFM in the treatment of TEN lesions.

Indexed as

extracellular matrixovine forestomach matrixre-epithelializationStevens-Johnson syndrometoxic epidermal necrolysis

Identifiers

PMID41658482
PMCPMC12880185

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.