Evidence map›Paper›PMID 41658459›Full record

ArticleTranslational andrology and urology2026

Low expression and significance of AOC1 in prostate adenocarcinoma.

Hong-Qun Wang, De-Lun Yan, Hao-Ming Hua, Cong Huang, Wei Sun, Ya-Nan Zhu, Na Yu, Jing Shen, Zhi-Hou Ma, Si-Zhen Tao and 3 more

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In one paragraph

Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hong-Qun WangDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
De-Lun YanDepartment of Surgery, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Hao-Ming HuaDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Cong HuangDepartment of Urological Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wei SunDepartment of Urological Surgery, the First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Ya-Nan ZhuDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Na YuDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Jing ShenDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Zhi-Hou MaDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Si-Zhen TaoDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Yan HuangDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
You-Jie GongDepartment of Pathology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.
Yang-Yang ZhangDepartment of Surgery, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical University, Bengbu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Currently, amine oxidase copper-containing 1 (AOC1) is less studied in cancer. There are few studies on the relationship between AOC1 and prognosis in prostate cancer. This study explores the expression profile of AOC1 in normal prostate tissue and prostate cancer, and investigates the relationship between the expression of AOC1 and prognosis of prostate cancer. Methods: The expression of AOC1 in 101 prostate cancer tissues and 22 normal prostate tissues was detected by immunohistochemistry. The AOC1 protein levels in the urine and blood samples of patients with prostate adenocarcinoma were examined by independent samples Results: AOC1 had a low positive expression rate (4.0%, 4/101) in prostate adenocarcinoma tissues, which was significantly lower than that (90.9%, 20/22) in adjacent normal tissues. The cancer-specific survival (CSS) for AOC1-positive patients was significantly shorter than AOC1-negative cases (31.750±8.384 Conclusions: AOC1 has low expression in prostate adenocarcinoma, and its positive expression may be associated with tumor prognosis.

Indexed as

Amine oxidase copper-containing 1 (AOC1)immunohistochemistryprognosisprostate adenocarcinoma

Identifiers

PMID41658459
PMCPMC12877924

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