ArticleJournal of oral biology and craniofacial research
Effect of dimethyl sulfoxide pretreatment on bonding of universal adhesives to pulp chamber dentin.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Influence of dimethyl sulfoxide on microtensile bond strength and surface morphology of tribochemically repaired nanohybrid composite: AnJournal of conservative dentistry and endodontics · 2026Article
- Effect of dimethyl sulfoxide on the resin-dentin bond strength of universal adhesives after thermocycling.Frontiers in dental medicine · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Aim and objective: To evaluate the effect of 50 % (v/v) dimethyl sulfoxide (DMSO) pretreatment on immediate (24 h) and delayed (6 months) microtensile bond strength (μTBS) of an etch-and-rinse adhesive and two universal adhesives to dentin. Materials and methods: A total of 144 extracted human molars were decoronated, pulp chambers exposed, and roots sectioned 2 mm apical to the CEJ. Teeth were randomly divided into six experimental groups (n = 24), based on surface pretreatment and adhesive system used: Group 1A: Adper Single Bond 2 (ASB) Group 2A: Tetric N-Bond Universal (TNBU) Group 3A: Prime & Bond Universal (PNBU) Groups 1B, 2B, and 3B received the same adhesives, respectively, following a 50 % (v/v) DMSO wet bonding pretreatment. All adhesives were applied per manufacturer's instructions, followed by composite resin build-up. Ten samples per group were tested for μTBS at 24 h and ten after 6 months of storage. Failure mode was analyzed. Four additional samples per group underwent SEM evaluation to observe the resin-dentin interface. Statistical analysis: Data were analyzed using one-way ANOVA and Tukey's post hoc test for intergroup comparisons. Unpaired t-tests were applied for two-group comparisons. Significance was set at p < 0.05. Results: DMSO pretreatment significantly improved both immediate and long-term μTBS (p < 0.05) across all adhesives. PNBU exhibited the highest bond strength at both time intervals. Conclusion: Dentin pretreatment with 50 % DMSO prior to adhesive application enhances immediate μTBS and preserves bond durability at 6 months, regardless of adhesive system used.
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