Evidence map›Paper›PMID 41658335›Full record

ArticleBJUI compass2026

Survival outcomes in prostate cancer patients treated at an Indian tertiary care centre.

Aswathy P, Sivaranjini Kannusamy, Amey Oak, Gagan Prakash, Amit Joshi, Vedang Murthy, Santosh Menon, Sandhya Cheulkar, Monika Lokhande, Ganesh Balasubramaniam and 3 more

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aswathy PHomi Bhabha National Institute Mumbai India.
Sivaranjini KannusamyHomi Bhabha National Institute Mumbai India.ORCID https://orcid.org/0000-0001-7414-8751
Amey OakHomi Bhabha National Institute Mumbai India.
Gagan PrakashHomi Bhabha National Institute Mumbai India.ORCID https://orcid.org/0000-0003-1722-4337
Amit JoshiHomi Bhabha National Institute Mumbai India.
Vedang MurthyHomi Bhabha National Institute Mumbai India.ORCID https://orcid.org/0000-0001-6011-9319
Santosh MenonHomi Bhabha National Institute Mumbai India.
Sandhya CheulkarHomi Bhabha National Institute Mumbai India.
Monika LokhandeHomi Bhabha National Institute Mumbai India.
Ganesh BalasubramaniamHomi Bhabha National Institute Mumbai India.
Rajesh DikshitHomi Bhabha National Institute Mumbai India.
Pankaj ChaturvediHomi Bhabha National Institute Mumbai India.
Sudeep GuptaHomi Bhabha National Institute Mumbai India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prostate cancer is an emerging public health concern in India, with rising incidence and varying survival outcomes. This study aimed to evaluate 5-year overall survival and identify prognostic factors among prostate cancer patients treated at Tata Memorial Hospital (TMH), Mumbai. Methods: This retrospective study included all patients newly diagnosed with prostate cancer between January and December 2017 who received cancer-directed treatment at TMH. Patients were followed through 2022. Clinico-epidemiological variables including age, PSA levels, Gleason grade, clinical extent (EAU risk group classification), intent, completion status and treatment modality were analysed. Kaplan-Meier survival curves and Cox proportional hazards models were used to assess survival outcomes. Results: A total of 421 patients were included, with a mean (SD) age of 66 ± (8.39) years and a median (IQR) PSA of 45.9 (17-154) ng/ml. All patients were symptomatic at presentation, predominantly with urinary complaints (90.5%), followed by bone pain (3.6%) or both (5.9%). At diagnosis, 15.2% had localized disease, 25.8% had locally advanced disease, and 58.4% had metastatic cancer. The overall 5-year survival rate was 61%. Prognostic factors significantly associated with survival included age, PSA, Gleason grade and disease extent. Patients with PSA > 1000 ng/ml had the poorest prognosis (33% 5-year survival). Survival varied by age group, declining from 66% in those aged 66-75 years to 45% in patients >75 years, although this trend was not statistically significant in adjusted analysis ( Conclusion: Survival in prostate cancer is strongly influenced by clinical extent at diagnosis, PSA, Gleason grade and treatment. Improving early detection, expanding multimodal treatment strategies and ensuring treatment completion are critical to enhancing outcomes in India.

Indexed as

Gleason gradeprostate cancerPSA levelsurvival

Identifiers

PMID41658335
PMCPMC12877309

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.