Evidence map›Paper›PMID 41658279›Full record

ArticleResuscitation plus2026

Evaluation of systemic and cerebral hemodynamics after systematic and early extracorporeal cardiopulmonary resuscitation in swine.

Julian San Geroteo, Ali Jendoubi, Fanny Lidouren, Naoto Watanabe, Yara Abi Zeid Daou, Alice Hutin, Lionel Lamhaut, Nadir Mouri, Bijan Ghaleh, Pierre-Louis Léger and 4 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Julian San GeroteoUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Ali JendoubiUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Fanny LidourenUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Naoto WatanabeUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Yara Abi Zeid DaouUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Alice HutinUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Lionel LamhautUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Nadir MouriAPHP, Hôpitaux Universitaires Henri Mondor, Département de Biochimie-Pharmacologie, 94000 Creteil, France.
Bijan GhalehUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Pierre-Louis LégerUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Jerome RambaudUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Rebecca GoutchtatUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Matthias KohlhauerUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.
Renaud TissierUniv Paris Est Créteil, INSERM, IMRB, F-94010 Créteil, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is thought to be efficient when performed promptly after cardiac arrest. However, its neurological benefit remains questionable if applied very early and systematically. Accordingly, we sought to compare systemic and cerebral hemodynamics when ECPR was implemented systematically compared to conventional cardiopulmonary resuscitation (CCPR) with epinephrine. Material and methods: Following 5 min of untreated ventricular fibrillation, pigs were randomly submitted to CCPR with epinephrine or crystalloid-primed ECPR after either a 10- or 30-min low-flow (4 groups: CCPR 10', ECPR 10', CCPR 30' and ECPR 30'. Defibrillations were then delivered until the return of spontaneous circulation (ROSC). Swine were followed 240 min from cardiopulmonary onset. Results: Six pigs were included in each group. Survival rate was higher in CCPR 10' group vs ECPR 10' (6/6 vs 2/6; Conclusions: The early and systemic implementation of ECPR after either a 10- or 30-min low-flow was associated with impaired cerebral and systemic hemodynamics after ROSC, as compared to CCPR with epinephrine.

Indexed as

Brain injuryCardiac arrestCerebral hemodynamicsEpinephrineExtracorporeal cardiopulmonary resuscitation

Identifiers

PMID41658279
PMCPMC12874813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.