Evidence map›Paper›PMID 41658278›Full record

ArticleResuscitation plus2026

Survival with one versus three centimeters of active decompression during automated head-up CPR in a porcine cardiac arrest model.

Pouria Pourzand, Anja Metzger, Johanna Moore, Bayert Salverda, Hamza Hai, Mithun Suresh, Sarah Bubier, Kerry Bachista, Nicolas Segond, Guillaume Debaty and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pouria PourzandDepartment of Emergency Medicine, Lehigh Valley Health Network, Bethlehem, PA, USA.
Anja MetzgerDepartment of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.
Johanna MooreDepartment of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.
Bayert SalverdaHennepin Healthcare Research Institute, Minneapolis, MN, USA.
Hamza HaiHennepin Healthcare Research Institute, Minneapolis, MN, USA.
Mithun SureshDepartment of Medicine, CentraCare-St. Cloud Hospital, St. Cloud, MN, USA.
Sarah BubierHennepin Healthcare Research Institute, Minneapolis, MN, USA.
Kerry BachistaMayo Clinic School of Health Sciences, Mayo Clinic in Florida, Jacksonville, FL, USA.
Nicolas SegondHennepin Healthcare Research Institute, Minneapolis, MN, USA.
Guillaume DebatyDepartment of Emergency Medicine, University of Grenoble Alps/CNRS/TIMC-IMAG UMR 5525, Grenoble, France.
Keith LurieDepartment of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Automated head-up (AHUP) CPR, combining controlled head/thorax elevation, active compression-decompression CPR, and an impedance threshold device, has shown improved survival with favorable neurological outcomes versus conventional (C) CPR. The optimal amount of active lift (AD) during AHUP-CPR to optimize survival remains unknown. This study focused primarily on 24-h survival with 1-cm of active lift (AL-1 cm) with a rectilinear waveform versus 3-cm of active lift (AL-3 cm) with a trapezoidal waveform during AHUP-CPR. Methods: Anesthetized pigs ( Results: ROSC occurred in 6/12 pigs with AL-1 cm vs 12/12 with AL-3 cm ( Conclusion: 24-h survival rates were significantly higher with AL-3 cm vs AL-1 cm during AHUP-CPR. Together with improved hemodynamics observed with AL-3 cm, these outcomes underscore the critical importance of AL-3 cm to optimize AHUP-CPR.

Indexed as

Active compression-decompression CPRCardiac arrestHeadUp CPRHemodynamicsImpedance threshold deviceSurvival

Identifiers

PMID41658278
PMCPMC12878586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.