Evidence map›Paper›PMID 41658266›Full record

ArticleJID innovations : skin science from molecules to population health2026

Dermoscopy-guided high-frequency ultrasound: Principles and applications in dermatology.

Mehdi Boostani, Ximena Wortsman, Giovanni Pellacani, Krisztián Füzesi, Mariano Suppa, Veronique Del Marmol, Florencia Vera Morandini, Javiera Perez-Anker, Priscila Giavedoni, Carmen Cantisani and 5 more

Abstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mehdi BoostaniDepartment of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Ximena WortsmanDepartment of Dermatology, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Giovanni PellacaniUOC of Dermatology, Department of Medical and Cardiological Science, University of "Sapienza" of Rome, Rome, Italy.
Krisztián FüzesiDermus, Budapest, Hungary.
Mariano SuppaDepartment of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Veronique Del MarmolDepartment of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Florencia Vera MorandiniDermatology Department, Hospital Clínic, Universidad de Barcelona, Barcelona, Spain.
Javiera Perez-AnkerDermatology Department, Hospital Clínic, Universidad de Barcelona, Barcelona, Spain.
Priscila GiavedoniDermatology Department, Hospital Clínic, Universidad de Barcelona, Barcelona, Spain.
Carmen CantisaniUOC of Dermatology, Department of Medical and Cardiological Science, University of "Sapienza" of Rome, Rome, Italy.
Lucas BoussingaultDepartment of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Miklós GyöngyDermus, Budapest, Hungary.
Gyorgy ParaghDepartment of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Kamran AvanakiRichard and Loan Hill Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, Illinois, USA.
Norbert KissDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional skin imaging modalities are often bulky, expensive, and impractical for routine dermatology practice. There is a need for a portable, multimodal imaging tool that integrates high-resolution surface and subsurface visualization at the point of care. The aim of this study was to describe the design, technical capabilities, and clinical application of dermoscopy-guided high-frequency ultrasound and to evaluate its performance across a range of dermatologic conditions. Dermoscopy-guided high-frequency ultrasound was applied to a total of 130 lesions from 122 patients at the Department of Dermatology, Semmelweis University (Budapest, Hungary); Université Libre de Bruxelles (Brussels, Belgium); and Hospital Clínic, Universidad de Barcelona (Barcelona, Spain). The examined cases included malignant skin cancers and inflammatory disorders. Dermoscopy-guided high-frequency ultrasound enabled simultaneous visualization and correlation of surface dermoscopic patterns with underlying structural alterations in real time. The device identified disease-specific imaging features for both malignant and inflammatory lesions. Artificial intelligence-based segmentation improved image interpretability. Dermoscopy-guided high-frequency ultrasound bridges a critical gap between surface and subsurface dermatologic imaging, offering a practical, portable, and cost-effective solution that could enhance noninvasive diagnosis and management in dermatologic care.

Indexed as

Dermoscopy-assisted high-frequency ultrasoundDermoscopy-guided high-frequency ultrasoundHigh-frequency ultrasoundImagingSkin cancer

Identifiers

PMID41658266
PMCPMC12874293

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.