Evidence map›Paper›PMID 41658173›Full record

ArticleACS omega2026

The Antithrombotic Potential of Sulfated-Polysaccharides from Red Seaweed

Caroline L Peixoto, Vitória Karoline F Monteiro, José Osmar S Júnior, Lucas L Bezerra, George Meredite C de Castro, Norberto de Kássio V Monteiro, Renato de Azevedo Moreira, Aline M A Martins, Ludmila Belayev, Reinaldo B Oriá

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caroline L PeixotoLaboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
Vitória Karoline F MonteiroLaboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
José Osmar S JúniorDepartment of Analytical Chemistry and Physical Chemistry, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
Lucas L BezerraDepartment of Analytical Chemistry and Physical Chemistry, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
George Meredite C de CastroDepartment of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
Norberto de Kássio V MonteiroDepartment of Analytical Chemistry and Physical Chemistry, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.ORCID https://orcid.org/0000-0002-5847-5733
Renato de Azevedo MoreiraDepartment of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.
Aline M A MartinsIntegrated Space Stem Cell Orbital Research (ISSCOR) Center/Sanford Consortium for Regenerative MedicineUCSD, Center for Novel Therapeutics, 9310 Athena Cir, Suite 200, La Jolla, California 92037, United States.
Ludmila BelayevNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, United States.
Reinaldo B OriáLaboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE 60020-181, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombosis has emerged as a significant concern during the Coronavirus Disease 2019 (COVID-19) pandemic, with patients experiencing increased venous thromboembolism due to prolonged immobilization and inflammation. In Brazil, studies show a higher thrombosis risk among COVID-19 patients, emphasizing the need for effective thromboprophylaxis. Heparin (HEP), commonly used in hospitals, enhances antithrombin III (ATIII) activity to inhibit thrombin and factor Xa, thus reducing thrombosis risk. However, it can cause adverse effects like bleeding and HEP-induced thrombocytopenia, complicating its use and prompting the search for safer anticoagulant alternatives. This study aimed to evaluate the anticoagulant properties of sulfated polysaccharides (SP) derived from the red seaweed

Identifiers

PMID41658173
PMCPMC12878786

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.