Evidence map›Paper›PMID 41658079›Full record

ArticleACS omega2026

Combined Biospectroscopy with Multivariate Analysis for the Differential Diagnosis of Leptospirosis Disease: A Pilot Study.

Alejandra Zambrano, Jorge Trilleras, Victoria Arana Rengifo, Kássio M G Lima, Ana Carolina Neves Menezes, Camilo L M Morais, Anne B Figueira Câmara, Roberto Jose García Álzate, Ismael Enrique Piñeres Ariza, Claudia Maria Elisa Romero Vivas and 3 more

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alejandra ZambranoDoctorado en Medicina Tropical, Universidad del Atlántico, Carrera 30 Número 8-49, Puerto Colombia, Barranquilla, Atlántico 1890, Colombia.ORCID https://orcid.org/0000-0001-8103-7611
Jorge TrillerasDoctorado en Medicina Tropical, Universidad del Atlántico, Carrera 30 Número 8-49, Puerto Colombia, Barranquilla, Atlántico 1890, Colombia.
Victoria Arana RengifoDoctorado en Medicina Tropical, Universidad del Atlántico, Carrera 30 Número 8-49, Puerto Colombia, Barranquilla, Atlántico 1890, Colombia.
Kássio M G LimaInstitute of Chemistry, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Ana Carolina Neves MenezesInstitute of Chemistry, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Camilo L M MoraisInstitute of Chemistry, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Anne B Figueira CâmaraInstitute of Chemistry, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Roberto Jose García ÁlzateDoctorado en Medicina Tropical, Universidad del Atlántico, Carrera 30 Número 8-49, Puerto Colombia, Barranquilla, Atlántico 1890, Colombia.
Ismael Enrique Piñeres ArizaDoctorado en Medicina Tropical, Universidad del Atlántico, Carrera 30 Número 8-49, Puerto Colombia, Barranquilla, Atlántico 1890, Colombia.ORCID https://orcid.org/0000-0003-4871-6211
Claudia Maria Elisa Romero VivasUniversidad del Norte, km 5 vía Puerto Colombia Área Metropolitana Barranquilla, Barranquilla 081007, Colombia.
Andrew K I FalconarUniversidad del Norte, km 5 vía Puerto Colombia Área Metropolitana Barranquilla, Barranquilla 081007, Colombia.
Margarett Cuello-PèrezUniversidad del Norte, km 5 vía Puerto Colombia Área Metropolitana Barranquilla, Barranquilla 081007, Colombia.
Carlos Andres Carmona PatiñoLaboratorio de Salud Pública Departamento del Atlántico, CL 40 No. 45 46, Barranquilla 080001, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, reported estimates indicate that there are 1.03 million annual cases of leptospirosis, with 58,900 deaths worldwide. The Pan American Health Organization (PAHO) in 2022 indicates that the febrile symptoms of leptospirosis are similar to other diseases such as influenza and dengue, among other diseases. Therefore, an early and accurate diagnosis of leptospirosis is essential for adequate and rapid treatment. In this study, attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy combined with multivariate analysis techniques was employed to classify between healthy controls and leptospirosis positive samples. Spectra from 113 dried blood plasma samples from patients (

Identifiers

PMID41658079
PMCPMC12878783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.