ReviewAmerican journal of cancer research2026
Mitochondria-related genes or proteins affect the progression of hepatocellular carcinoma: roles, mechanisms and potential treatments.
Review in American journal of cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- ADCK1 Regulates Mitochondrial Bioenergetics in Hepatocellular Carcinoma In Vitro.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondria-related genes or proteins can affect various functional indicators of mitochondria, encompassing ATP synthesis, the generation of reactive oxygen species, and the intricate process of mitochondrial autophagy. Numerous researches have unveiled a profound association between mitochondrial dysfunction and the onset, progression, and prognosis of hepatocellular carcinoma. In recent years, a large number of studies have conducted experiments on mitochondria-related genes or proteins to explore their roles and mechanisms in causing mitochondrial functional changes and thereby influencing the progression of hepatocellular carcinoma. Over the past five years, a plethora of studies have been meticulously conducted on mitochondria - related genes and proteins. The aim is to precisely define their functions and the underlying molecular mechanisms in triggering mitochondrial functional aberrations, thereby affecting the progression of HCC. This review is dedicated to comprehensively recapitulating the pertinent progress made in the past half - decade. Additionally, it will delve into how these factors can present feasible and prospective therapeutic modalities for the management of HCC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.