Evidence map›Paper›PMID 41657787›Full record

ArticleAmerican journal of cancer research2026

Pretreatment nodal SUVmax predicts neck progression in hypopharyngeal cancer undergoing definitive chemoradiotherapy, while higher radiotherapy dose improves regional control particularly in the high SUV-N subgroup: a long-term outcome study.

Wing-Keen Yap, Chia-Hsin Lin, Ken-Hao Hsu, Po-Yuan Chen, Chien-Yu Lin, Shin-Nan Lin, Nai-Ming Cheng, Kai-Ping Chang, Chung-Jan Kang, Chi-Kuang Young and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Physiological uptake patterns of gastric lymph node stations onQuantitative imaging in medicine and surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wing-Keen YapDepartment of Radiation Oncology, Proton and Radiation Therapy Center, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chia-Hsin LinDepartment of Radiation Oncology, Proton and Radiation Therapy Center, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Ken-Hao HsuDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Po-Yuan ChenDepartment of Radiation Oncology, Proton and Radiation Therapy Center, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chien-Yu LinDepartment of Radiation Oncology, Proton and Radiation Therapy Center, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Shin-Nan LinDepartment of Medical Imaging and Intervention, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Nai-Ming ChengDepartment of Nuclear Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Kai-Ping ChangDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chung-Jan KangDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chi-Kuang YoungDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chi-Ting LiauDepartment of Medical Oncology, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Yi-An LuDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Yu-Feng HuDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Chia-Chi YehDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.
Ting-Shiuan YehDepartment of Otolaryngology, Head and Neck Surgery, New Taipei Municipal Tu-Cheng Hospital New Taipei City 236, Taiwan.
Tsung-You TsaiDepartment of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University Kwei-Shan, Taoyuan City 333, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study evaluated the prognostic significance of pretreatment maximum standardized uptake value of the primary tumor (SUV-T) and the metastatic lymph nodes (SUV-N) in 146 patients with lymph node-positive hypopharyngeal squamous cell carcinoma (HPSCC) treated with definitive chemoradiotherapy between 2005 and 2013. Pretreatment

Indexed as

18F-FDG PET/CTdefinitive chemoradiotherapydose-escalationHypopharyngeal squamous cell carcinomanodal SUVmaxprognostic factorregional controlsurvival outcomes

Identifiers

PMID41657787
PMCPMC12877375

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.