Evidence map›Paper›PMID 41657731›Full record

ArticleFrontiers in medical technology2026

Evaluation of liposome

Piriya Chonsut, Weeratian Tawanwongsri, Jomkarn Naphatthalung, Julalak Chokpaisarn, Rawiwan Charoensup, Panupong Puttarak, Siau Hui Mah, Atitaya Roumwong, Lavanya Goodla, Auemphon Mordmuang

Abstract read
In one paragraph

Article in Frontiers in medical technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Piriya ChonsutDepartment of Applied Thai Traditional Medicine, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.
Weeratian TawanwongsriDepartment of Dermatology, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.
Jomkarn NaphatthalungTraditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Songkhla, Thailand.
Julalak ChokpaisarnTraditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Songkhla, Thailand.
Rawiwan CharoensupSchool of Integrative Medicine, Mae Fah Luang University, Chiang Rai, Thailand.
Panupong PuttarakDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Siau Hui MahSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Malaysia.
Atitaya RoumwongDepartment of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Lavanya GoodlaDepartment of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM, United States.
Auemphon MordmuangDepartment of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Encapsulating herbal extracts with wound-healing properties in liposomes may enhance their stability and delivery performance. This study evaluated the biological efficacy of a liposome-encapsulated ethanolic extract of Methods: The ethanolic extract was incorporated into liposomes using the thin-film hydration method. Anti-inflammatory activity was assessed in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Cell viability and migration were evaluated in normal human dermal fibroblasts (NHDFs). Results: LEC significantly reduced TNF-α and IL-1β production in a dose-dependent manner and enhanced fibroblast viability and migratory capacity compared with the crude extract and vitamin E controls. In vivo, topical LEC markedly accelerated wound contraction, achieving 99.9 ± 0.1% closure by Day 12, which was significantly greater than the normal saline-treated control ( Conclusion: These findings indicate that liposomal encapsulation enhances the bioactivity of

Indexed as

anti-inflammatoryCentella asiaticadrug deliveryliposomeproliferative activitywound healing

Identifiers

PMID41657731
PMCPMC12876173

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.