Evidence map›Paper›PMID 41657620›Full record

ArticleBioinformation2025

Managing medication-related osteonecrosis of jaw: A prospective observational study.

Mahendra Kumar Dadarwal, Timbadiya Vijaykumar Mansukhbhai, Nishad Gawali, Pradeep Kumar Dohare, Sumit Bhatt, Swati Kharat, Rashmi Laddha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahendra Kumar DadarwalDepartment of Oral Surgery, Rajasthan Dental College, Jaipur, Rajasthan, India.
Timbadiya Vijaykumar MansukhbhaiDepartment of Oral Pathology and Microbiology, Rishiraj College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Nishad GawaliDepartment of Public Health Dentistry, Hazaribag College of Dental Sciences and Hospitals, Hazaribagh, Jharkhand, India.
Pradeep Kumar DohareDepartment of Community Medicine, SRVS Medical College, Shivpuri, Madhya Pradesh, India.
Sumit BhattDepartment of Oral and Maxillofacial Surgery, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.
Swati KharatDepartment of Prosthodontics, Dr RR Kambe Dental College and Hospital, Akola, Maharashtra, India.
Rashmi LaddhaDepartment of Prosthodontics, Dr RR Kambe Dental College and Hospital, Akola, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) remains a significant clinical challenge due to its complex etiology and variable response to treatment. This prospective observational study evaluated the effectiveness of current management protocols in 130 patients receiving antiresorptive or antiangiogenic therapies. Patients were assessed clinically and radiographically and treated according to standardized stage-specific guidelines. Combined conservative and surgical interventions achieved better healing rates, symptom control, and improved quality of life over 12 months. These findings support ongoing refinement of stage-based MRONJ protocols to optimize therapeutic outcomes and patient care.

Indexed as

antiresorptive therapybone healingconservative treatmentjaw osteonecrosismanagement protocolsMedication-related osteonecrosis of the jaw (MRONJ)surgical intervention

Identifiers

PMID41657620
PMCPMC12880135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.