ArticleBioinformation2025
Effect of propolis extract and chlorhexidine in treating chronic periodontitis: A randomized controlled trial.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Chronic periodontitis remains a significant dental health issue, with current treatments often relying on chemical irrigants like chlorhexidine, which may have limitations. Therefore, it is of interest to compare the clinical and microbiological effects of 0.2% chlorhexidine (CHX) and 25% propolis extract as subgingival irrigants adjunctive to scaling and root planing in chronic periodontitis patients. Twenty patients were randomly assigned to receive either CHX or propolis following SRP. Significant improvements were observed in clinical parameters (Gingival Index, Plaque Index and Probing Pocket Depth) and microbiological reduction in both groups, with propolis showing superior results. Propolis extract exhibited greater efficacy in reducing clinical symptoms and bacterial detection, suggesting it as a promising natural alternative to CHX.
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