Evidence map›Paper›PMID 41657604›Full record

ArticleBioinformation2025

Evaluation of neurological outcomes after prolonged sedation among ICU patients: A prospective study in India.

Kishore Sekar, Hasan Saleem Manghi, Hadiya Shakil

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kishore SekarDepartment of General Surgery, Queens Hospital, London, Romford, United Kingdom.
Hasan Saleem ManghiDepartment of Intensive Care/Accidents and Emergency, Eterna Health, Sindh, Pakistan.
Hadiya ShakilDepartment of Accident & Emergency, Dr. Ziauddin Hospital, Sindh, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extended sedation in intensive care settings can produce neurological problems. Hence, this prospective study analyzed the neurological recovery of patients receiving continuous sedation (> 72 hours). Neurological function was evaluated at the time of ICU discharge and at three months to assess for any residual cognitive or functional impairment. Most patients appeared to recover completely and achieve their baseline pre-morbid function although a small number had mild persistent cognitive impairment. The data suggest that with continued vigilance after prolonged sedation greater than 72 hours there are generally no significant long-term neurological implications, which can be useful to render safer sedation methods in critical care medicine.

Indexed as

cognitive recoveryintensive care unitneurological outcomesprospective studySedation

Identifiers

PMID41657604
PMCPMC12880142

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.