Evidence map›Paper›PMID 41657590›Full record

ArticleBioinformation2025

Prognostic significance of CD44s expression in oral squamous cell carcinoma: An immuno-histo-chemical analysis.

Hershita Singh, Sandeep Sidhu, Arun Bhardwaj, Arpit Sharma, Mamta Sharma, Shivendra Rana

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hershita SinghDepartment of Oral Pathology and Microbiology, National Dental College, DeraBassi, Mohali, Punjab, India.
Sandeep SidhuDepartment of Oral Pathology and Microbiology, Maharaja Ganga Singh Dental College and Research Centre, Sriganganagar, Rajasthan, India.
Arun BhardwajDepartment of Oral Pathology and Microbiology, Swami Devi Dyal Hospital & Dental College, Golpura, Barwala, Panchkula, India.
Arpit SharmaDepartment of Medical Administration, Homi Bhabha Cancer Hospital, Sangrur, Punjab, India.
Mamta SharmaDepartment of Oral Pathology and Microbiology, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.
Shivendra RanaDepartment of Oral Pathology and Microbiology, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is a common malignancy with a poor prognosis, highlighting the need for reliable molecular biomarkers. CD44s, a cell adhesion molecule, has been implicated in tumor progression, but its prognostic role in OSCC is unclear. This retrospective study evaluated CD44s expression in 50 OSCC cases using immunohistochemistry and an immunoreactive scoring system. High CD44s expression significantly correlated with advanced stage, lymph node metastasis and poor histological grade. CD44s overexpression may serve as a prognostic biomarker to identify high-risk OSCC patients requiring aggressive therapy.

Indexed as

CD44sclinical stageimmunohistochemistrylymph node metastasisOral squamous cell carcinomaprognostic markertumor differentiation

Identifiers

PMID41657590
PMCPMC12880162

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