Evidence map›Paper›PMID 41657551›Full record

ArticleFrontiers in physiology2026

Chronic heat stress compromises egg production and quality parameters through changes in blood biochemistry and uterine gene expression in laying hens raised under cage-free environment.

Bikash Aryal, Shuja Majeed, Bikas R Shah, Nimra Khalid, Lingying Zhao, Lisa Bielke, Qiuhong Wang, Ali Nazmi

Abstract read
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bikash AryalDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.
Shuja MajeedDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.
Bikas R ShahDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.
Nimra KhalidDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.
Lingying ZhaoDepartment of Food, Agricultural, and Biological Engineering, The Ohio State University, Columbus, OH, United States.
Lisa BielkePrestage Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC, United States.
Qiuhong WangDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.
Ali NazmiDepartment of Animal Sciences, College of Food, Agricultural and Environmental Sciences, The Ohio State University, Wooster, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat stress (HS) possesses a significant threat to poultry production systems, compromising bird health, performance, and profitability. As the egg industry transitions from conventional cage systems to cage-free (CF) systems, understanding the physiological and production impacts of HS is important. This study evaluated the effects of chronic cyclic HS on egg production, egg quality, blood biochemical parameters and shell gland gene expression in commercial laying hens raised in CF housing system. A total of 240 Hy-Line W-36 hens (26 weeks old) were randomly assigned to thermoneutral (TN, 22 °C) or HS conditions (35 °C for 12 h/day, 22 °C for 12 h/day) for 8 weeks. Each treatment included six pens (20 hens/pen; 0.139 m

Indexed as

blood biochemistrycage-freeegg productiongene expressionheat stress

Identifiers

PMID41657551
PMCPMC12875927

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.