ArticleWorld journal of otorhinolaryngology - head and neck surgery2026
Age-Adjusted Charlson Comorbidities Index for Survival Prognosis in Laryngeal Squamous Cell Carcinoma Patients.
Article in World journal of otorhinolaryngology - head and neck surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
Objective: This study aimed to explore the prognostic relevance of the age-adjusted Charlson Comorbidity Index (ACCI) in laryngeal squamous cell carcinoma (LSCC) survival. Methods: This retrospective analysis was conducted on the medical records of 367 LSCC patients admitted to the First Hospital of Shanxi Medical University, China, from January 2012 to December 2015. The cohort ( Results: In this cohort of 367 LSCC patients, the 5-year overall survival (OS) rate was 58.6%. Meanwhile, the 5-year progression-free survival (PFS) rate was 64.3%, and the cancer-specific survival (CSS) rate was 61.9%. Cox regression analysis identified ACCI, T stage, distant metastasis, and degree of differentiation as independent risk factors for both OS and CSS ( Conclusions: Overall, this study advances our understanding of ACCI's prognostic significance and its role in guiding LSCC management to improve clinical outcomes.
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