Evidence map›Paper›PMID 41657231›Full record

ArticleSoft matter2026

Tiny plastic, big trouble: how polystyrene nanoparticles impact DNA-damage repair deficient cervical cancer cells.

Jordan D Berezowitz, Mira C Fish, Lauren E Mehanna, Breanna Knicely, Claire E Rowlands, Eva M Goellner, Brittany E Givens

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Soft matter, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jordan D BerezowitzDepartment of Chemical and Materials Engineering, Stanley and Karen Pigman College of Engineering, University of Kentucky, Lexington, USA. brittany.givens@uky.edu.ORCID http://orcid.org/0009-0004-2839-2015
Mira C FishDepartment of Chemical and Materials Engineering, Stanley and Karen Pigman College of Engineering, University of Kentucky, Lexington, USA. brittany.givens@uky.edu.
Lauren E MehannaDepartment of Chemical and Materials Engineering, Stanley and Karen Pigman College of Engineering, University of Kentucky, Lexington, USA. brittany.givens@uky.edu.
Breanna KnicelyDepartment of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, USA.
Claire E RowlandsDepartment of Chemical and Materials Engineering, Stanley and Karen Pigman College of Engineering, University of Kentucky, Lexington, USA. brittany.givens@uky.edu.
Eva M GoellnerDepartment of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, USA.
Brittany E GivensDepartment of Chemical and Materials Engineering, Stanley and Karen Pigman College of Engineering, University of Kentucky, Lexington, USA. brittany.givens@uky.edu.ORCID http://orcid.org/0000-0002-6386-7766

Funding

Pilot Project ProgramP30ES026529 · NIEHS · UNIVERSITY OF KENTUCKY · PI Erin N Haynes · 2017 to 2026
$15.4M
NIEHS NIH HHS P30 ES026529
6 · The paper itself

Abstract

Microplastics are becoming increasingly abundant waste products; therefore, the risk of human exposure is also increasing. The cytotoxic consequences of microplastic exposure, particularly in cancer, have yet to be explored. We obtained commercially available polystyrene nanoparticles of uniform size (86.61 ± 6.41 nm) and confirmed the chemical composition and shape using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM), respectively. We evaluated colloidal stability over a range of concentrations from 1-1000 µg mL

Indexed as

DNA DamageDNA RepairMicroplasticsNanoparticlesPolystyrenesUterine Cervical NeoplasmsCell SurvivalFemaleHeLa CellsHumansMicroplasticsPolystyrenes

Identifiers

PMID41657231
PMCPMC12884371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.