Evidence map›Paper›PMID 41656714›Full record

ReviewThe plant pathology journal2026

Control Strategies of Plant Viruses Using Spray-Induced Gene Silencing.

Seung-Kook Choi, Eseul Baek, Ho-Jong Ju, Francisco Tenllado, Ju-Yeon Yoon

Abstract readReview
In one paragraph

Review in The plant pathology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seung-Kook ChoiVirology Unit, Department of Horticultural and Herbal Environment, National Institute of Horticultural and Herbal Science, RDA, Wanju 55365, Korea.
Eseul BaekDepartment of Plant Protection and Quarantine, Jeonbuk National University, Jeonju 54896, Korea.
Ho-Jong JuDepartment of Agricultural Biology, Jeonbuk National University, Jeonju 54896, Korea.
Francisco TenlladoDepartment of Biotechnology, Margarita Salas Center for Biological Research, Spanish National Research Council, Madrid 28040, Spain.
Ju-Yeon YoonDepartment of Plant Protection and Quarantine, Jeonbuk National University, Jeonju 54896, Korea.

Funding

Jeonbuk National UniversityRural Development Administration RS-2025-02263567
6 · The paper itself

Abstract

Plant viruses severely limit global crop productivity, yet no pesticide-like antiviral agents are currently available for effective control. Double-stranded RNA (dsRNA) technologies, acting through RNA interference, provide a sequence-specific and non-transgenic strategy to suppress viral replication and have emerged as promising non-transgenic solutions for crop protection. Spray-induced gene silencing (SIGS), which applies externally produced dsRNA through foliar sprays, seed treatments, or root uptake, provides practical advantages over genetic modification, including rapid deployment, environmental compatibility, and target specificity. Recent advances in industry-scale dsRNA production and nanomaterial-based formulations have improved dsRNA stability, uptake, and persistence in planta, supporting the feasibility of field application. However, major challenges persist, such as rapid environmental degradation, restricted systemic mobility, high production costs, and unresolved biosafety and regulatory issues. Overcoming these challenges will require innovations in cost-effective and scalable in vitro RNA production, protective formulations, and precision delivery technologies, alongside comprehensive ecological risk assessments. Finally, this review emphasizes current technological advances of SIGS, integrating with nanotechnology and other reliable field application methodologies. Taken together, these advances position dsRNA-based technologies as a realistic and transformative platform for next-generation, sustainable plant virus management.

Indexed as

controldouble-strand RNAplant virusesRNA interferencespray-induced gene silencing

Identifiers

PMID41656714
PMCPMC12884052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.