Evidence map›Paper›PMID 41656585›Full record

Trial reportTechnology in cancer research & treatment

Effect of Ultrasound Combined with Microbubbles on Blood Perfusion in Invasive Breast Cancer-A Prospective Clinical Trial.

Yunyun Dong, Daqing Zhang, Wei Feng, Yuqing Huang, Zhicheng Ge, Xian-Quan Shi

Abstract readClinical Trial
In one paragraph

Trial report in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunyun DongDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0009-0007-0069-3213
Daqing ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0009-0002-9569-7244
Wei FengDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0009-0004-7874-2933
Yuqing HuangDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-6254-5124
Zhicheng GeDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-4407-9964
Xian-Quan ShiDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0009-0002-0488-212X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionBlood perfusion insufficiency and hypoxia are the main causes of drug resistance to chemotherapy in breast cancer. Increasing blood perfusion can improve drug delivery. This study aimed to investigate the effects of ultrasound-stimulated microbubbles (USMBs) on hemoperfusion in invasive breast cancer (IBC).MethodsIn this prospective clinical trial, 36 patients diagnosed with IBC were enrolled sequentially. The treatment group (n = 18, enrolled from June 2022 to April 2025) were treated with SonoVue

Indexed as

Breast NeoplasmsMicrobubblesUltrasonic TherapyAdultContrast MediaFemaleHumansMiddle AgedNeoplasm InvasivenessProspective StudiesTreatment OutcomeUltrasonographyContrast Mediablood perfusionbreast cancerdrug deliverymicrobubblesultrasound

Identifiers

PMID41656585
PMCPMC12883721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.