Observational studyNeurosurgical review2026
Comparison of microsurgical and endovascular treatment outcomes in poor-grade aneurysmal subarachnoid hemorrhage: a multicenter cohort study.
Observational study in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The optimal treatment for poor-grade aneurysmal subarachnoid hemorrhage (aSAH) remains controversial. This study compared outcomes of microsurgical treatment (MST) and endovascular treatment (EVT) in poor-grade aSAH. We consecutively enrolled patients with poor-grade aSAH admitted to the Chinese Multicenter Aneurysm Database (CMAD) between January 2017 and December 2020. After 1:1 propensity score matching (PSM), clinical outcomes and in-hospital complications were compared between MST and EVT. Generalized estimating equations (GEE) assessed outcome associations; Kaplan–Meier and Cox models analyzed survival and mortality predictors. Of 1,008 patients, 373 MST cases were matched to 373 EVT cases. Mortality was similar between groups (28.1% vs. 27.5%, p = 0.075). EVT was associated with lower rates of dependent survival at discharge (41.8% vs. 59.1%, adjusted OR 0.584, p < 0.001) and at 2 years (21.3% vs. 31.8%, adjusted OR 0.574, p = 0.026), shorter length of stay (17 vs. 20 days, adjusted OR 0.053, p = 0.025), and fewer intracranial infections (4.8% vs. 13.9%, adjusted OR 0.248, p = 0.001). However, hydrocephalus was more frequent in the EVT group (9.7% vs. 4.6%, adjusted OR 2.294, p = 0.001). Risk factors for mortality differed between groups. In this multicenter observational cohort of patients with poor-grade aSAH, MST and EVT were associated with similar survival, whereas EVT was associated with more favorable functional outcomes, shorter hospitalization, and fewer intracranial infections, but a higher incidence of hydrocephalus. These findings support individualized treatment selection while highlighting the need for cautious interpretation given potential residual confounding.
Indexed as
Identifiers
41656448What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.