Evidence map›Paper›PMID 41656415›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Characterization of prophage carrying bla

Patricia Marie-Jeanne Lievens, Roberta Galavotti, Luca Caiazzo, Laura Macacaro, Caterina Signoretto, Paolo Gaibani

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patricia Marie-Jeanne LievensDepartment of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.
Roberta GalavottiDepartment of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.
Luca CaiazzoDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, Strada Le Grazie 8, Verona, 37134, Italy.
Laura MacacaroMicrobiology and Virology Unit, Azienda Ospedaliera Universitaria Integrata Di Verona, Verona, 37134, Italy.
Caterina SignorettoDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, Strada Le Grazie 8, Verona, 37134, Italy.
Paolo GaibaniDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, Strada Le Grazie 8, Verona, 37134, Italy. paolo.gaibani@univr.it.

Funding

Università degli Studi di Verona FUR2024
6 · The paper itself

Abstract

Here we characterized the genome on a K. pneumoniae strain carrying the blaKPC-184 variant and the integrated prophage regions. Genomic analysis showed that the KP-OL-VR-24 strain belonged to the ST307 and carried a variant of blaKPC-3, named blaKPC-184. Sequence alignment showed that KPC-184 differed by KPC-3 by E274D substitution. Of note, blaKPC-184 gene was embedded in a prophage region showing a high homology with p45-lncX3 plasmid. Our findings highlighted the role of prophages in the dissemination of the blaKPC gene, thus emphasizing the need for molecular surveillance to control the diffusion of public health threats.

Indexed as

beta-LactamasesKlebsiella InfectionsKlebsiella pneumoniaeProphagesGenome, BacterialHumansItalyPlasmidsbeta-LactamasesBlaKPC-184KPC variantsProphage regionsSurveillanceWhole-genome sequencing

Identifiers

PMID41656415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.