Evidence map›Paper›PMID 41656298›Full record

ReviewMicrosystems & nanoengineering2026

Droplet microfluidics for biomedical applications: emerging trends and future developments.

Li Ma, Xiong Zhao, Junsheng Hou, Yaxuan Xiao, Xinlan Lu, Zhenzhen Chen, Jinjia Wei, Nanjing Hao

Abstract readReview
In one paragraph

Review in Microsystems & nanoengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li MaSchool of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China.
Xiong ZhaoSchool of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China.
Junsheng HouSchool of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China.
Yaxuan XiaoKey Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, School of Mechanical Engineering, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China.
Xinlan LuDepartment of Gastroenterology, First Affiliated Hospital of Xi'an Jiaotong University, 710049, Xi'an, Shaanxi, P.R. China.
Zhenzhen ChenNanofluids Technologies Co. Ltd, 712000, Xi'an, Shaanxi, P.R. China.
Jinjia WeiSchool of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China.
Nanjing HaoSchool of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, 710049, Xi'an, Shaanxi, P.R. China. nanjing.hao@xjtu.edu.cn.ORCID http://orcid.org/0000-0003-3808-7941

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22108212
6 · The paper itself

Abstract

Droplet-based microfluidics has witnessed tremendous progress in the past two decades, and this technique has been demonstrated as one of the most promising technologies to synthesize high-end and versatile materials with advanced functions, which provide great possibilities for numerous applications. Herein, the recent progress in preparing high-value natural microspheres by droplet-based microfluidic techniques is summarized comprehensively. We start with an in-depth articulation of the working principles of droplet-based microfluidics and surface modification for microdevices. Subsequently, droplet-based microspheres' fabrication methods have been discussed and summarized. Furthermore, the emerging representative biomedical applications of the different types of natural microspheres are outlined systematically. After that, we consider the challenges that hinder droplet-based microfluidic improvement in academic and industrial applications. Eventually, we will point out the perspectives of droplet-based microfluidics and aim to advance droplet-based microfluidics and sophisticated applications. The scope of this review is not only to offer an in-depth understanding of droplet-based microfluidics but also to open new pathways for versatile applications.

Identifiers

PMID41656298
PMCPMC12883628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.