Evidence map›Paper›PMID 41656163›Full record

SynthesisJournal of gastroenterology and hepatology2026

Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations.

Sanjiv Mahadeva, Kewin Tien Ho Siah, Uday C Ghoshal, Hidekazu Suzuki, Yeong Yeh Lee, Kee Huat Chuah, Vincent Chung, Linda Zhong, Benjamin Wei-Rong Tay, Ban Hong Ang and 19 more

Abstract readConsensus StatementSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Sanjiv MahadevaDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-5824-0590
Kewin Tien Ho SiahDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Uday C GhoshalInstitute of Gastrosciences and Liver Transplantation, Apollo Multispeciality Hospitals, Kolkata, India.ORCID https://orcid.org/0000-0003-0221-8495
Hidekazu SuzukiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.ORCID https://orcid.org/0000-0002-8994-6163
Yeong Yeh LeeSchool of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.ORCID https://orcid.org/0000-0002-6486-7717
Kee Huat ChuahDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-9811-7546
Vincent ChungJC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China.ORCID https://orcid.org/0000-0002-5947-4492
Linda ZhongSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Benjamin Wei-Rong TayDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID https://orcid.org/0000-0002-9000-2936
Ban Hong AngDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Ram Prasad SinnanaiduDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Tao BaiDivision of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0001-9697-8510
Tadayuki OshimaDepartment of Gastroenterology, Okazaki City Medical Association, Public Health Center, Okazaki, Aichi, Japan.
Tanisa PatcharatrakulCenter of Excellence in Neurogastroenterology and Motility, Faculty of Medicine, Chulalongkorn University and Division of Gastroenterology, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Sanjeev SachdevaDepartment of Gastroenterology, GB Pant Hospital, New Delhi, India.ORCID https://orcid.org/0000-0002-5588-1111
Ping-Huei TsengEndoscopic Division, Department of Integrated Diagnostic & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-7483-7538
Jinsong LiuDivision of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yinglian XiaoDepartment of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Ratha-Korn VilaichoneCenter of Excellence in Digestive Diseases and Gastroenterology Unit, Department of Medicine and Thailand Science Research and Innovation Fundamental Fund 2025, Thammasat University, Klong Luang, Pathumthani, Thailand.
Joon Seong LeeInstitute for Digestive Research, Digestive Disease Center, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Jung-Hwan OhDepartment of Internal Medicine, Eunpyeong St. Marys Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ari Fahrial SyamDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Ching Liang LuEndoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan.
Tiing Leong AngDepartment of Gastroenterology and Hepatology, Changi General Hospital, Singapore.ORCID https://orcid.org/0000-0001-9993-8549
In-Kyung SungDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0002-3848-5571
Xiao-Hua HouDivision of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0002-3694-2126
Kentaro SuganoDepartment of Internal Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Justin WuDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR.
Hiroto MiwaDepartment of Medicine, Kawanishi City Medical Center, Kawanishi, Hyogo, Japan.ORCID https://orcid.org/0000-0001-9844-642X

Funding

Abbott LaboratoriesAsian Neurogastroenterology and Motility Association (ANMA)
6 · The paper itself

Abstract

backgroundFunctional dyspepsia (FD) is a common gastrointestinal disorder that significantly impacts patients' quality of life. Over a decade ago, the Asian Neurogastroenterology and Motility Association (ANMA) and the Asian Pacific Association of Gastroenterology (APAGE) jointly developed the first Asian consensus report on FD. In this consensus report, members of ANMA and APAGE provide updated recommendations on the definition, diagnosis, epidemiology, pathophysiology, and management of FD, focusing on Asian populations.

methodsThe task force members conducted a systematic literature review and used a modified Delphi process to develop updated consensus statements. Based on members' feedback, statements that failed to reach at least 80% consensus in the first round of voting were revised. Revisions included rephrasing for clarity, incorporating additional evidence, and subgroup voting during a second round of discussion at a hybrid meeting.

resultsThe task force developed 32 statements covering key aspects of FD. Major updates include new insights into the pathophysiology and emerging treatment options. The task force acknowledged that the limited scope and heterogeneity of available studies limit definitive conclusions about the utility of some emerging therapies such as probiotics and potassium-competitive acid blockers in FD management.

conclusionsThe second Asian Consensus Report on FD provides updated evidence-based recommendations to improve the diagnosis and management of FD in clinical practice, particularly in the Asian setting.

Indexed as

DyspepsiaAsiaAsian PeopleDelphi TechniqueEvidence-Based MedicineHumansQuality of LifeAsiaconsensusdiagnosisepidemiologyfunctional dyspepsiamanagementpathophysiology

Identifiers

PMID41656163
PMCPMC12969256

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.